Homegrown Covivac vaccine to begin second phase of trials on August 10
Vietnam’s second homegrown Covivac candidate vaccine will begin the second stage of clinical trials in the northern province of Thai Binh’s Vu Thu district on August 10.
Vietnam’s second homegrown Covivac candidate vaccine (Photo: VNA)
Hanoi (VNA) - Vietnam’s second homegrown Covivac candidate vaccine will begin the second stage of clinical trials in the northernprovince of Thai Binh’s Vu Thu district on August 10.
A total of 375 volunteers will be classified in three groups for the 3mcg and 6 mcg dosages and placebo injections.
Earlier, assessing the first stage of Covivac human trialson over 120 volunteers since March 15, the National Ethics Committee inBiomedical Research under the Ministry of Health concluded that the vaccine wassafe, well tolerated, immunogenic, and eligible for the second stage.
Covivac has been developed and produced by the Institute of Vaccines and Medical Biologicals (IVAC). It usesprimary chicken embryo cell culture - a technique the institute used previouslyto successfully produce seasonal flu vaccines.
Associate Professor, Dr. Vu Dinh Thiem, director of the NIHE’s clinicaltrial center, said that the selected volunteers must be over 18 years old,possibly up to 70-80 years old, including those with chronic diseases such asdiabetes, hypertension but under stable treatment.
If the second stage goes well, by the end of September, the researchteam will collect blood samples from the volunteers on the 42nd day after their first jabs to evaluate the vaccine’s immunogenicity.
On the 57th day, the volunteers will continue to undergophysical examination and take blood tests for evaluation and analysis beforethe team proposes the third stage of trials on 1,000 volunteers./.
Since the COVID-19 outbreak, the Health Ministry has directed units to study and clinically test made-in-Vietnam vaccines while seeking technological transfer from abroad to proactively fight the pandemic in the country.
Prime Minister Pham Minh Chinh has assigned the Ministry of Science and Technology to coordinate the research and production of COVID-19 vaccines within the national product development programme by 2030 amid complicated developments of the pandemic nationwide.
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This case marks the ninth fetal cardiac intervention conducted in HCM City, and it was considered the most technically demanding to date due to the fetus’s extremely early gestational age and the severity of the condition as diagnosed with aortic atresia.
The groundbreaking ceremony took place one day after the VNVC Vaccine JS Company and Sanofi Group exchanged cooperation documents on vaccine production technology transfer under the witness of State President Luong Cuong and French President Emmanuel Macron.
Vietnam’s traditional medicine took centre stage at the International Congress Biopharm Nonclinical Development, BioNCiD 2025, held on May 25-26 in the Cuban city of Varadero, amid growing global interest in sustainable healthcare solutions.
Under the agreement, VNVC and Sanofi will gradually implement technology transfers to enable domestic production of several key Sanofi vaccines that are widely used in Vietnam. In addition, Sanofi will support VNVC in training human resources and quality management in vaccine research and manufacturing.
Despite the ongoing global circulation and unpredictable developments of SARS-CoV-2, the World Health Organisation (WHO) hasn’t issued new warnings about COVID-19, said the Ministry of Health.
Vietnam’s second homegrown Covivac candidate vaccine (Photo: VNA) 
