Singapore to start clinical trials for monoclonal antibody against COVID-19
Singapore will begin human clinical trials to evaluate TY027, a monoclonal antibody (mAb) that specifically targets SARS-CoV-2, the virus which causes COVID-19 next week.
Singapore (VNA) - Singapore will begin human clinicaltrials toevaluate TY027, a monoclonal antibody (mAb) that specifically targets SARS-CoV-2,the virus which causes COVID-19 next week.
The trialsof TY027, developed by Singapore-based biotechnology company Tychan, willbe conducted on 23 healthy individuals for a potential treatment for COVID-19. It aims to slow theprogression of the disease and accelerate recovery, as well as for itspotential to provide temporary protection against infection with SARS-CoV-2.
Thefirst phase of the trials will be carried out by the SingHealth InvestigationalMedicine Unit for about six weeks to determine the safety and effectiveness ofTY027.
If this phase is successful, Tychan will seek approval for the antibody to beadministered to a larger population of volunteer patients in subsequent trials.
ProfessorOoi Eng Eong of Duke-NUS Medical School, who is one of the founders of Tychan,said that TY027 could be used not only to treat COVID-19 patients but also toprevent infections.
"If the drug is indeed safe enough, we could, for instance,give (it) to healthcare workers who are treating COVID-19 patients so theydon't get the infections themselves.
"And, as well as other scenarios like, for instance, if onetravels to places with a lot of COVID-19 cases, this could be used to preventinfections when they are away from Singapore," he said.
Monoclonal antibodies are immune system proteins that arecreated in the laboratory, and can be specially designed and engineered totarget SARS-CoV-2./.
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Illustrative image (Source: The Strait Times) 
